«Grey zone» of heart failure

The grey zone of truth.

Registration of new drugs and devices, and our guidelines for management of cardiovascular disease, are mostly based on the results of clinical trials. Trial results are reported in great detail, with primary and secondary endpoints, event rates in the relevant treatment groups, relative risks or odds ratios with confidence intervals, and the corresponding statistical analyses. However, the bus...

Assessment of the grey zone: a comparison of two methods in heart failure patients awaiting cardiac resynchronization therapy

Background ICD implantation is known to improve prognosis in patients with ischemic cardiomyopathy (ICM). Determining which patients are at high risk of ventricular arrhythmias and sudden death remains difficult. The presence and extent of grey zone detected by CMR has been linked to ventricular arrhythmias and may be useful in determining which patients should have an ICD. Several processing m...

Hodgkin’s lymphoma and Grey-zone lymphomas

Grey Zone Lymphomas: Lymphomas with Intermediate Features

The current classification of lymphoid neoplasms is based on clinical information, morphology, immunophenotype, and molecular genetic characteristics. Despite technical and scientific progress, some aggressive B-cell lymphomas with features overlapping between two different types of lymphomas remain difficult to classify. The updated 2008 World Health Organization (WHO) classification of Tumour...

Effect of walking at home on heart functioning levels of people with heart failure

Background and Objectives: Heart failure is more common in the elderly than in the general population. Among the non-drug treatments, the easiest and most comprehensible method is direct implementation of sports program. Due to high cost of hospital care for patients with heart failure and complications, this study examined the effects of walking as a form of rehabilitation program. The subject...